15 August 2022: UK : Gov.UK epidemiological situation
Cases of monkeypox infection were confirmed in England from 6 May 2022. The outbreak has mainly been in gay, bisexual, and men who have sex with men without documented history of travel to endemic countries. Further details on the epidemiology are available in the monkeypox technical briefing.
To expand the UK’s capability to detect monkeypox cases, some NHS laboratories are now testing suspected monkeypox samples with an orthopox polymerase chain reaction (PCR) test (orthopox is the group of viruses which monkeypox is part of). Since 25 July 2022, the monkeypox case definition recognises those who are orthopox-positive as highly probable cases, and those who test positive on a monkeypox PCR test as confirmed cases. The counts below combine both of these categories.
Up to 15 August 2022 there were 3,081 confirmed and 114 highly probable monkeypox cases in the UK: 3,195 in total. Of these, 75 were in Scotland, 27 were in Northern Ireland, 43 were in Wales and 3,050 were in England.
Table 1: Number of confirmed and highly probable monkeypox cases by UK nation of residence, 6 May to 15 August 2022
UK nation Total* Confirmed* Highly Probable*
England 3,050 (+167) 2,936 (+156) 114 (+11)
Northern Ireland 27 (+2) 27 (+2) 0
Scotland 75 (+6) 75 (+6) 0
Wales 43 (+3) 43 (+3) 0
Total 3,195 (+178) 3,081 (+167) 114 (+11)
*The numbers in brackets show change since last report (8 August 2022)
A high proportion of England cases were London residents (71%, 2,141 of 3,036 with location information). For confirmed and highly probable cases in the UK, where gender information was available, 3,131 (98.8%) were men and 39 were women. The median age of confirmed and highly probable cases in the UK was 36 years (interquartile range 31 to 44).
Table 2: Number of confirmed and highly probable monkeypox cases by region of residence, England, 6 May to 15 August 2022
Region of residence Total confirmed and highly probable cases Change since last report
East of England 109 +2
East Midlands 43 +2
London 2,141 +94
North East 37 +5
North West 180 +19
South East 281 +23
South West 80 +6
West Midlands 98 +7
Yorkshire and Humber 67 +8
Under investigation** 14 +1
Total 3,050 +167
**Address not yet confirmed. Negative changes due to updates to location information.
Data sources
Monkeypox surveillance data in England is currently compiled daily, based on monkeypox and orthopox virus test results from the Rare and Imported Pathogens Laboratory (RIPL), which is the UK Health Security Agency (UKHSA) monkeypox reference laboratory, and other UK laboratories with monkeypox and orthopox testing. This is combined with case information recorded by local Health Protection Teams in the UKHSA national case management system.
Counts of confirmed cases in Wales, Northern Ireland, and Scotland are submitted to UKHSA by Public Health Wales, Public Health Agency Northern Ireland, and Public Health Scotland respectively.
Information about this publication
These figures are used for official reporting of monkeypox confirmed case counts in the UK.
England counts may differ from those published in the Notifications of infectious diseases (NOIDs) causative agents weekly report. This is due to differences in timings of when the data is compiled, and differences in processing of duplicate data (for example, if a person has tested more than once but insufficient information is provided to identify them).





